It's killer for germs! We use this spray with confidence on our hands (and many other places) knowing there is no chemical residue left behind on the skin. This spray is made purely with 12 different essential oils of the highest quality! Bonus - it doesn't dry out the skin. Other than hands, we use it in public restrooms, airplanes, yoga mat, outside of kids' backpacks and lunch bags, cell phones, TV remotes, inside gym bags and shoes.